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SoClean vs Clean Zone (2021): Which CPAP Cleaner is Better?

Continuous positive airway pressure (or CPAP) machines are super helpful for people living with obstructive sleep apnea. The pressure that CPAP machines exert help prevent the collapse of the upper airways of its users. Such a handy device will inevitably see a lot of use, and with a lot of use comes a lot of cleaning to do.

To keep your machine clean and yourself healthy and free of microbes that might grow on your equipment, you have to use a CPAP cleaner. These cleaners work in different ways: some use ultraviolet (UV) light to disinfect, while others wash the CPAP apparatuses with water.

This comparison will focus on two cleaners, the SoClean 2 and Clean Zone, that use another method of disinfection: activated oxygen or ozone. Details about how they work, the design of each product, and more can be found below.

SoClean vs Clean Zone Comparison Chart

ModelSoClean 2 Clean Zone
PriceCheck Price at SoClean.comCheck Price at CleanZoneNow.com
MechanismActivated oxygenActivated oxygen
Dimensions11″ x 11″ x 13″4.5″ x 2.5″ x 2″
Power Source110-240 VACRechargeable lithium-ion battery
DisplayFront display, indicator lightsIndicator lights


Clean Zone places an emphasis on being lightweight and compact, while SoClean 2’s frame is sturdier and more stable.

SoClean receives hose insertion on both sides, while Clean Zone accentuates its petite size and weight.

Clean Zone’s most striking feature is its miniscule size: a mere 4.5 by 2.5 inches, which is significantly smaller than its competitors. This small cleaner is powered by a rechargeable lithium-ion battery, which can be charged using the same USB charger that a lot of phones use nowadays. It notifies you about the end of one CPAP cleaning cycle, when its battery is low, and other machine conditions by its light, which changes colors depending on the situation.

Clean Zone has one hose port and comes with two universal hose adapters, making it usable for nearly every CPAP machine available on the market. However, Clean Zone’s compact main body isn’t the only thing you need for it to run as it should. Your CPAP machine’s empty water reservoir and mask with the hose attached have to be placed in the included zip-locked plastic bag with the Clean Zone. This means that while Clean Zone’s dimensions really are small, the set-up will still take up as much space as your mask, hose, and reservoir require.

The SoClean 2 on the other hand looks bulkier, but it provides a stable, fixed cleaning experience. The hose can be attached on either side of the SoClean machine, so it’s ideal for bedside placing regardless of what side of the bed you prefer to sleep on.

Its big chamber can also easily store your mask in one solid fixed container. Adapters for widely used CPAP machines like the ResMed AirSense 10 and AirCurve 10 are also available online, so the SoClean 2 can still be used even if the included universal adapters don’t work for your specific machine.

One thing that sets the SoClean apart from the Clean Zone is its front display that shows the cleaning time elapsed and other details. It’s big enough for even elderly customers to read the screen easily, but not big enough to be a cumbersome addition.

Ease of Use

Clean Zone starts at the press of a button, but doesn’t provide as much feedback on cleaning as the SoClean 2.

A Clean Zone inside its sanitizing bag (left) and an open SoClean chamber (right).

Both the Clean Zone and SoClean 2 are easy to use, especially if you compare them to manually cleaning your CPAP machine. However, this ease shows in different ways for each cleaner. Clean Zone’s user-friendliness can be experienced through a literal push of a button. It requires only one button push to start cleaning once the set-up is prepared inside the CPAP sanitizer bag that comes with the Clean Zone.

The light turns blue to signify the start of the cycle. Afterwards, the Clean Zone beeps to tell you that it’s finished, then it automatically turns off. It works the same way if your CPAP machine’s water reservoir is not detachable. You simply have to connect the hose to the cleaner, and put the Clean Zone inside a large cleaning zip bag with the whole CPAP machine.

In contrast, the SoClean 2’s ease of use manifests in its design. Your CPAP mask that needs cleaning can fit snugly inside the cleaning chamber, connected to the hose and CPAP machine. Because it’s protected by the SoClean’s solid case, there’s less possibility of damaging any important parts compared to when it’s placed in a plastic bag.

The screen also tells you the current time and at what time you’ve set the cleaner to run, compared to the Clean Zone’s beep which only sounds at the end of the cycle. The SoClean is also easily operable: just pop your mask in when it’s time to clean. It’s also foolproof, since it doesn’t operate if the mask, hose, or slot plug isn’t present.

Clean Zone has a very quick cleaning cycle at only 30 minutes. However, this is a preset timer. In comparison, the SoClean 2 is programmable. It allows the user to choose the time of cleaning and how long each cleaning cycle will take.

In terms of customer support, SoClean sports a slight edge over its competitor. They have FAQs available at their website, and SoClean maintenance bundles, which contain a replacement kit for the cartridge filter and a neutralizing pre-wash, are also available for purchase online. SoClean also has a 30 day trial period and comes with a 2 year warranty. To its credit, the Clean Zone does also have a 60 day money back guarantee for customers in the continental US.


Both machines are highly effective at sanitizing the important CPAP components.

The Clean Zone’s basic pack (left) and the SoClean 2 (right).

Both the SoClean 2 and the Clean Zone claim to kill 99% of all microbes that might be residing in your CPAP mask, hose, and machine. This is because both products use the same method of disinfection: ozone, also called activated oxygen. Ozone is a naturally occurring gas that has been used in food-grade and medical-grade cleaning for a long time now. It has been proven that ozone is able to kill practically all known microbes in the air, which is highly useful for breathing-related equipment like CPAP machines. The two machines’ designs also ensure that ozone cannot leak into the room while the machine is at use, instead staying within the designated bag or chamber for cleaning.

The activated oxygen method of cleaning provides a bigger guarantee of effective cleaning after even a short cleaning cycle when compared to some other procedures. Both cleaning machines also operate relatively quietly, ensuring that it causes as little disturbance as it can. However, it should be noted that some users say the ozone can damage some parts of the mask. Despite that, some doctors still recommend using ozone CPAP cleaning machines over other methods like wipes or soap and water because it’s more guaranteed to kill almost all microbes and no drying is required after cleaning.


Clean Zone and SoClean cater to different kinds of people with obstructive sleep apnea.

Clean Zone

A good fit for those on the go


The best bedside CPAP cleaner

For those who find that they are always out and about, the Clean Zone provides an effective way of cleaning your CPAP machine while travelling. Its USB-rechargeable battery and easily stowable sanitizing bag, along with the travel bag that comes with the set, makes sure that you can sleep well even away from home.

For almost everyone else though, the SoClean 2 is a better pick. It’s just as effective, and has added capabilities like a programmable timer and a front screen display. Trading portability for additional functions wouldn’t be a problem for people whose career or way of life doesn’t entail much travelling. Also, its dual hose port feature ensures that the SoClean 2 isn’t completely immovable and inflexible in a home setting.

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Rhodaline Escala-Phelps

Former Managing Editor and Team Leader at Compare Before Buying. Writer and researcher passionate about food, people, product comparisons, culture, and current events.